Clinical Trials

Clinical Trials

High Cholesterol & Statin Medication Intolerant Clinical Trial

Trial summary   

The purpose of this research study is to test if an investigational non-statin medication, compared to a placebo, is safe and effective for reducing major cardiovascular disease events in patients who are statin intolerant. Approximately 12,604 participants are planned for this study with a treatment period between 2 to 5 years.  There will be 6 office visits at the study center. Then after month 6, participants will alternate between telephone visits and in-clinic visits every 3 months until the end of the study.

Key inclusion criteria

  • Statin intolerant (unable to tolerate full recommended doses of medications like Lipitor®/atorvastatin and Crestor®/Rosuvastatin)
  • High LDL cholesterol
  • History of or high risk for cardiovascular disease (heart attack, stroke, peripheral arterial disease, etc.)

Compensation for time and travel

Our research patients are closely monitored by our cardiologists, nurses and research team. The study medication and all study-related procedures and physical exams are provided to you at no cost. You will be reimbursed $50 for each study visit. Valet parking is provided at no cost. 

About cardiovascular disease and statin intolerance

Cardiovascular disease is the leading cause of death in the western world. High LDL cholesterol is a major modifiable risk factor in the development of cardiovascular disease. Statin medications can help lower LDL cholesterol, but it is estimated that approximately 10% of patients who are prescribed statins are considered statin intolerant.

Click the button below to complete a pre-qualification form, or call 651-326-4448 for more information.

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